Since being established, Confluence has worked with and on behalf of a wide range of clients and partner organisations. These include:

Arts Council England; the Association of Chief Executives of Voluntary Organisations (ACEVO); the Association of Chief Police Officers (ACPO); the Association of Child Psychotherapists; Barnet, Enfield and Haringey Mental Health Trust; Centre for Mental Health; Children in Need; The Clink Charity; Clinks; Comic Relief; Department for Digital, Culture, Media and Sport (DCMS); Glasgow School of Social Work; Hertfordshire Partnership University NHS Foundation Trust; the Home Office; the Independent Custody Visiting Association (ICVA); IOD PARC; London Borough of Haringey; London Borough of Lambeth; London Borough of Tower Hamlets; HMP/YOI Holloway; HMP Wandsworth; LankellyChase Foundation; London Probation Trust; The Liberty Choir; Mind; the Northern School of Child and Adolescent Psychotherapy (NSCAP); the National Centre for Applied Learning Technologies (NCALT); The National Policing Improvement Agency (NPIA); Offender Health Collaborative; Office of the Police and Crime Commissioner for Gloucestershire; Office of the Police and Crime Commissioner for North Yorkshire; Only Connect; Porticus UK; Real Insight; Resolving Chaos; Revolving Doors Agency; RIFT Social Enterprise; the Shaftesbury Partnership; Spark Inside; St. Giles Trust; Sussex Partnership NHS Foundation Trust; Time to Change; Together, For Mental Wellbeing.